| LPC | Licensed Professional Counselor |
| LPC | Legal Practice Course (UK) |
| LPC | Linear Predictive Coding |
| LPC | Linear Predictive Coding (Speech Processing) |
| LPC | Landmarks Preservation Commission (New York City, NY) |
| LPC | Legal Practice Companion |
| LPC | Las Positas College (Livermore, CA) |
| LPC | Liberal Party of Canada |
| LPC | Low Pin Count |
| LPC | Low Pressure Carburizing (vacuum furnaces) |
| LPC | Low Power Consumption |
| LPC | Low Pay Commission (UK) |
| LPC | Legacy Printer Controller |
| LPC | Link Protocol Converter |
| LPC | lysophosphatidylcholine |
| LPC | Liquid Particle Counter (semiconductors) |
| LPC | Local Procedure Call |
| LPC | Line Printer Control |
| LPC | Local Planning Committee (various organizations) |
| LPC | Latinas Promoviendo Comunidad (Spanish: Promoting Latina Community; aka Lambda Pi Chi Sorority) |
| LPC | Lucky People Center (Swedish artistic collective) |
| LPC | Loss Prevention Council (UK) |
| LPC | Lexington Presbyterian Church (South Carolina) |
| LPC | Libertarian Party of Canada |
| LPC | Local Pharmaceutical Committee (United Kingdom) |
| LPC | Low-Pressure Compressor |
| LPC | Louisiana-Pacific Corporation (various locations) |
| LPC | Loss Prevention Certification (Loss Prevention Foundation) |
| LPC | Luftfahrt-Presse-Club (German: Aviation Press Club) |
| LPC | Least-Preferred Co-Worker |
| LPC | Liberia Peace Council (political group) |
| LPC | Learning Policy Center (University of Pittsburgh, PA) |
| LPC | Life Pentecostal Church (various locations) |
| LPC | Ligand-Protein Contact |
| LPC | Laser Particle Counter |
| LPC | Lesotho People’s Congress |
| LPC | Les Pensions Complémentaires (French) |
| LPC | Late Payment Charge |
| LPC | Libertarian Party of California |
| LPC | Lower Predicate Calculus (mathematics) |
| LPC | Less Paper in the Cockpit (Airbus) |
| LPC | Low Particle Concentration |
| LPC | Lahore Press Club (Lahore, Pakistan) |
| LPC | Lesson Plan Creator (educational software company) |
| LPC | Lipocortin |
| LPC | Liquid-Borne Particle Counter |
| LPC | Lafayette Presbyterian Church (Florida) |
| LPC | Laser Physics Centre (Australia) |
| LPC | Lansdale Presbyterian Church (Landsdale, PA) |
| LPC | Lighting Playback Controller (theater lighting systems) |
| LPC | Looks, Personality, Closeness |
| LPC | Linksys Partner Connection (Cisco) |
| LPC | Long-Period Comet |
| LPC | Licence Proficiency Check (UK aviation) |
| LPC | Laboratoire de Purification Chimique (French: Chemical Purification Laboratory) |
| LPC | L-propionylcarnitine |
| LPC | Laboratory for Paleoclimatology and Climatology (University of Ottawa, ON, Canada) |
| LPC | Leather Personnel Carrier (boots) |
| LPC | Linear Predictive Coefficient |
| LPC | Launch Pod Container |
| LPC | Longitudinal Parity Check |
| LPC | Little People of Canada |
| LPC | Low Pressure Chamber Technician (US Navy) |
| LPC | Laser Power Controller |
| LPC | Lamp Post Cache (geocaching) |
| LPC | Local Processing Center |
| LPC | Lam-Platzman Correction |
| LPC | Limiting Permissible Concentrations |
| LPC | Liquor Picis Carbonis (Latin: Coal Tar Solution) |
| LPC | LandPro Corporation (Houston, TX) |
| LPC | Loi de Protection du Consommateur (French: Consumer Protection Law; Canada) |
| LPC | Low Order Path Connection |
| LPC | LAN Party Coalition (gaming) |
| LPC | Lazy People Company |
| LPC | Linear Programming Classification |
| LPC | Light Paraffin Conversion |
| LPC | Local Proxy Cache |
| LPC | List Process Company |
| LPC | Livestock and Poultry Commission (Arkansas) |
| LPC | Local Procurement Contract |
| LPC | Lighthouse Power Controller (Coast Guard) |
| LPC | Logarithmic Polar Coordinate |
| LPC | Livermore Projects Committee |
| LPC | Light Post Cache (geocaching) |
| LPC | Lurker Player Character |
| LPC | Low Power Command |
| LPC | Low-Power Characterization |
| LPC | Low Pressure Container |
| LPC | Log Port Connection |
| LPC | Life Profit Center (insurance industry) |
| LPC | Light Production Color (market segment for printers) |